Researchers find gene that may be responsible for left ventricular noncompaction

2nd December 2016

Scientists say they have discovered a gene with mutations that may be responsible for left ventricular non compaction cardiomyopathy (LVNC).

The association between mutations on the gene obscurin and LVNC has been found by a team at the University of Colorado in America.

The researchers looked at nearly 5,000 genes in 335 patients with cardiomyopathy and found that several people with LVNC had a mutation in obscurin which affects how muscles contract.

Their findings have been published in the Journal of the American College of Cardiology

Researcher Dr Teisha Rowland said: "Left ventricular noncompaction is thought to happen during early human development. It would be interesting to see if mutated obscurin affects heart formation during development."

Dr Rowland said the findings pointed to areas where more research was needed, and she expected they would ultimately improve our understanding of the disease.

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