For midwives

Presentations from the 2016 Cumbria Conference

Dr Sarah Vause from St Mary’s Hospital in Manchester talks about identifying cardiomyopathy in patients who are pregnant.

Maternal Deaths from Cardiomyopathies – lessons learnt


Dr Adrian Brodison, Consultant Cardiologist and Clinical Lead for Cardiology, at University of Hospitals Morecambe Bay Foundation Trust, talks about the effects of cardiomyopathy on pregnancy.

Physiology clinical examination and echocardiography in normal pregnancy



European Society of Cardiology Guidelines

ESC Clinical Practice Guidelines on the management of cardiovascular disease during pregnancy.
ESC Guidelines on the management of cardiovascular diseases during pregnancy. The Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).
European Heart Journal (2011); 32, 3147 – 3197
Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.
AL Caforio et al
Eur Heart J (2013); 34(33):2636-48
Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society or Cardiology Working group on peripartum cardiomyopathy.
K Sliwa et al
European Journal of Heart Failure (2010); 12, 767 – 788
European Cardiomyopathy Pilot Registry: EURObservational Research Programme of the European Society of Cardiology.
P Elliott et al
European Heart Journal (2015)
ESC Textbook of Cardiovascular Medicine, containing a chapter on pregnancy and heart disease.

Other research and resources

A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy.
D Hilfiker-Kleiner et al
Cell (2007); 128(3): 589-600
Association of Fibrosis With Mortality and Sudden Cardiac Death in Patients With Nonischemic Dilated Cardiomyopathy.
A Gulati et al 
JAMA (2013); 309(9):896-908
Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
IS Patten et al
Nature (2012); 485(7398): 333-8
The Carvedilol Hibernation Reversible Ischaemia Trial: Marker of Success (CHRISTMAS).
JGF Cleland et al
The European Journal of Heart Failure (1999); 191-196
Clinical Outcomes for Peripartum Cardiomyopathy in North America: Results of the IPAC Study (Investigations of Pregnancy-Associated Cardiomyopathy).
DM McNamara et al
J Am Coll Cardiol (2015); 25:66(8): 905-14
Clinical Profile and Predictors of Complications in Peripartum Cardiomyopathy.
S Goland et al
Journal of Cardiac Failure (2009); Vol 15 Issue 8: 645-650
Dual Coronary Emboli in Peripartum Cardiomyopathy.
LC Box, V Hanak & JG Arciniegas
Tex Heart Inst J (2004); v31(4): 442-444
Echocardiographic Evaluation in Asymptomatic Relatives of Patients with Dilated Cardiomyopathy Reveals Preclinical Disease.
NG Mahon et al
Ann Intern Med (2005); 143(2):108-115
Managing palpitations and arrhythmias during pregnancy.
D.L Adamson & C Nelson-Piercy
Heart (2007); 93:1630-1636
National Perinatal Epidemiology Unit, featuring the results of the MBRRACE-UK: Mothers and Babies Reducing Risk through Audits and Confidential Enquiries across the UK report. 
Peripartum Cardiomyopathy: A Review.
D Pankaj
J Obstet Gynecol India (2010); Vol 60, No 1: 25-32
Peripartum cardiomyopathy: popuations-based birth prevalence and 7-year mortality.
MA Harper, RE Meyer & CJ Berg
Obstet Gynecol (2012); 120(5):1013-9
Predictors of pregnancy complications in women with congenital heart disease.
W Drenthen et al
European Heart Journal (2010); 31, 2124–2132
Pregnancy-associated cardiomyopathy: clinical characteristics and comparison between early and late presentation.
U Elkayam et al
Circulation (2005); 111:2050
Prophylactic Defibrillator Implantation in Patients with Nonischemic Dilated Cardiomyopathy.
A Kadish et al
N Engl J Med (2004); 350:2151-2158
Prospective multicenter study of pregnancy outcomes in women with heart disease.
SC Siu et al
Circulation. (2001); 104(5):515-21
The relationship between pre-eclampsia and Peripartum cardiomyopathy: a systematic review and meta-analysis.
N Bello, IS Hurtado Rendon, Z Arany
JACC (2013); Vol 62, Issue 18
Reports on Confidential Enquiries into Maternal Deaths: management strategies based on trends in maternal cardiac deaths over 30 years.
S Malhotra & SM Yentis
Int J Obstet Anesth (2006); 15(3):223-6
Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation Carriers – A European Cohort Study.
IAW van Rijsingen et al
Journal of the American College of Cardiology (2012); Vol. 59, No. 5.
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.
JS Ware et al
N Engl J Med (2016); 374:233-241
Systematic review of pregnancy in women with inherited cardiomyopathies.
SP Krul et al
Eur J Heart Fail (2011); 13(6):584-94
Truncations of Titin Causing Dilated Cardiomyopathy.
DS Herman et al
N Engl J Med (2012); 366:619-628